Styrene

Styrene

SCHEMBL7213574

C=C(CC)C(=O)OCCCCCC.C=CC(=O)OCCCC.C=Cc1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.50
HPGD P15428 1/20 0.50
ALDH1A1 P00352 3/20 0.43
CYP3A4 P08684 2/20 0.43
LMNA P02545 1/20 0.42
THRB P10828 3/20 0.41
THRA P10827 1/20 0.41
KDM4E B2RXH2 2/20 0.40
HCAR2 Q8TDS4 2/20 0.40
TP53 P04637 1/20 0.40
MAPK1 P28482 1/20 0.40
APP P05067 3/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 1/20 0.38
POLB P06746 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL491216 0.93 TSHR (0.48) TSHRALDH1A1CYP3A4LMNAKDM4E
Styrene SCHEMBL7210426 0.93 TSHR (0.44) TSHRHPGDALDH1A1CYP3A4LMNA
Styrene SCHEMBL10533310 0.92 TSHR (0.45) TSHRALDH1A1CYP3A4LMNATHRB
Styrene SCHEMBL11208181 0.90 TSHR (0.56) TSHRALDH1A1CYP3A4LMNAKDM4E
Styrene SCHEMBL5484779 0.90 TSHR (0.51) TSHRHPGDALDH1A1CYP3A4LMNA
Styrene SCHEMBL11607106 0.89 KDM4E (0.44) TSHRHPGDALDH1A1CYP3A4LMNA
Styrene SCHEMBL7534099 0.89 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4LMNA
Styrene SCHEMBL138332 0.89 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4LMNA
Styrene SCHEMBL5864244 0.89 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4LMNA
Styrene SCHEMBL6910235 0.89 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6617387-B2 Hydraulic binder polymeric dispersion of acrylic copolymers comprising 2 to 15% ionic or polar monomers; low glass transition temperature; stability; flexibility; no nitrogen containing monomers BASF AKTIENGESELLSCHAFT (DE) 2003-09-09 US disclosed
US-20020049265-A1 Ammonia-free polymer dispersions as additives in mineral building materials based on hydraulic binders BASF AKTIENGESELLSCHAFT (DE) 2002-04-25 US disclosed
US-6372287-B1 APPLYING TO MINERAL MOLDING AQUEOUS FILM-FORMING FORMULATION COMPRISING ETHYLENICALLY UNSATURATED ESTER MONOMER AND AT LEAST ONE DIFFERENT MONOETHYLENICALLY UNSATURATED MONOMER; NONFLUORESCENT, WEATHERPROOFING BASF AKTIENGESELLSCHAFT (DE) 2002-04-16 US disclosed
US-6162505-A Coating mineral moldings BASF AKTIENGESELLSCHAFT (DE) 2000-12-19 US disclosed
US-6074794-A COLOR AND BINDER FOR TONERS ON TRANSFER SHEET RICOH COMPANY, LTD. (JP) 2000-06-13 US disclosed
US-4789614-A BENZENE SULFONATE DICARBOXYLATE ANION; ELECTROSTATOGRAPHY EASTMAN KODAK COMPANY (US) 1988-12-06 US disclosed