Styrene

Styrene

SCHEMBL5484779

C=C(CC)C(=O)OC(=O)O.C=CC(=O)OCCCC.C=Cc1ccccc1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.51
HPGD P15428 1/20 0.51
THRB P10828 5/20 0.42
TDP1 Q9NUW8 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 4/20 0.38
CYP3A4 P08684 3/20 0.38
ATM Q13315 1/20 0.37
THRA P10827 1/20 0.37
APP P05067 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
MAPK1 P28482 2/20 0.36
TP53 P04637 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL7213574 0.90 TSHR (0.50) TSHRHPGDTHRBTDP1KDM4E
Styrene SCHEMBL8974528 0.89 TSHR (0.55) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL28887747 0.88 TSHR (0.67) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL3196230 0.88 TSHR (0.67) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL3696057 0.88 TSHR (0.67) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL67823 0.88 TSHR (0.67) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL8320579 0.85 TSHR (0.56) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL11607106 0.85 KDM4E (0.44) TSHRHPGDTDP1L3MBTL1KDM4E
Styrene SCHEMBL28616597 0.85 TSHR (0.59) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL3111143 0.85 TSHR (0.63) TSHRHPGDTHRBTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7291437-B2 Toner processes XEROX CORPORATION (US) 2007-11-06 US disclosed
US-7186494-B2 Toner processes XEROX CORPORATION (US) 2007-03-06 US disclosed
US-6841329-B2 Preparation of toner compositions by a chemical process, such as emulsion aggregation, wherein latex particles are aggregated with a colorant, and optional components, such as a wax XEROX CORPORATION (US) 2005-01-11 US disclosed
US-20040202951-A1 Toner processes XEROX CORPORATION 2004-10-14 US disclosed
US-20040202950-A1 Toner processes XEROX CORPORATION. 2004-10-14 US disclosed
US-20040202952-A1 Toner processes XEROX CORPORATION 2004-10-14 US disclosed
US-6803166-B2 Toner processes XEROX CORPORATION 2004-10-12 US disclosed
US-20040162373-A1 Toner processes XEROX CORPORATION 2004-08-19 US disclosed
US-6447974-B1 SEMICONTINUOUS EMULSION POLYMERIZATION PROCESS FOR PREPARING TONER PARTICLES WHEREIN THE LATEX IS FORMED BY EMULSION POLYMERIZATION IN THE PRESENCE OF AN ANIONIC SURFACTANT; EXCELLENT IMAGE UNIFORMITY XEROX CORPORATION 2002-09-10 US disclosed