Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565978 | 0.84 | CHRM1 (0.40) | CHRM1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL7212322 | 0.84 | CHRM1 (0.40) | CHRM1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL3265562 | 0.70 | MEN1 (0.39) | CHRM1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL19625907 | 0.68 | KCNH2 (0.46) | MEN1KMT2AALDH1A1KCNH2TSHR | |
| SCHEMBL7160283 | 0.68 | MEN1 (0.38) | MEN1KMT2ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11337783 | 0.68 | MEN1 (0.42) | MEN1KMT2ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL1074604 | 0.68 | TDP1 (0.47) | CHRM1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL13505469 | 0.67 | KCNH2 (0.45) | MEN1KMT2ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11332526 | 0.67 | KCNH2 (0.45) | MEN1KMT2ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL5138095 | 0.65 | HRH3 (0.41) | MEN1KMT2ATDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620940-B1 | Heterocyclic nitrogen/sulfur compounds used as chemical intermediates for drugs such as 3-chloro-4-(furan-2-yl)-1,2,5 -thiadiazole | ELI LILLY AND COMPANY | 2003-09-16 | — | — | US | disclosed |