SCHEMBL5138095

SCHEMBL5138095

CCCCc1nc(CCCC)c(CCCC)nc1CCCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.41
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB1 P18505 1/20 0.39
GABRG2 P18507 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRA5 P31644 1/20 0.39
GABRA3 P34903 1/20 0.39
GABRA2 P47869 1/20 0.39
GABRB2 P47870 1/20 0.39
GABRA4 P48169 1/20 0.39
GABRE P78334 1/20 0.39
GABRA6 Q16445 1/20 0.39
GABRG1 Q8N1C3 1/20 0.39
GABRG3 Q99928 1/20 0.39
GABRQ Q9UN88 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TSHR P16473 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3709649 0.84 GABRP (0.33) HRH3GABRPGABRDGABRA1GABRB1
SCHEMBL10496040 0.79 NOS2 (0.38) HRH3GABRPGABRDGABRA1GABRB1
SCHEMBL6162687 0.79 MAPK1 (0.38) NOS2ALDH1A1MAPK1GAA
SCHEMBL19625907 0.77 KCNH2 (0.46) MEN1KMT2ATSHRKCNH2ALDH1A1
SCHEMBL23352499 0.75 KDM4E (0.45) HRH3GABRPGABRDGABRA1GABRB1
SCHEMBL10496068 0.75 NOS2 (0.35) HRH3GABRPGABRDGABRA1GABRB1
SCHEMBL15440689 0.75 NOS2 (0.35) HRH3GABRPGABRDGABRA1GABRB1
SCHEMBL1187437 0.75 HPGD (0.35) HRH3GABRPGABRDGABRA1GABRB1
SCHEMBL13505896 0.75 KCNH2 (0.45) MEN1KMT2ATSHRLMNAKCNH2
SCHEMBL12251371 0.73 CASP1 (0.41) HRH3TSHRLMNAKCNH2NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2859961-A2 Methods and compositions for metal nanoparticle treated surfaces Avent, Inc. (US) 2015-04-15 EP disclosed
EP-1991365-B1 METHODS FOR FORMING SILVER-NANOPARTICLE TREATED SURFACES KIMBERLY CLARK CO (US) 2014-12-24 EP disclosed
US-20130122321-A1 Methods and Compositions for Metal Nanoparticle Treated Surfaces KIMBERLY-CLARK WORLDWIDE, INC. (US) 2013-05-16 US disclosed
US-8361553-B2 Methods and compositions for metal nanoparticle treated surfaces KIMBERLY-CLARK WORLDWIDE, INC. (US) 2013-01-29 US disclosed
US-7473446-B2 Retarder and circular polarizer FUJIFILM CORPORATION (JP) 2009-01-06 US disclosed
EP-1991365-A2 METHODS AND COMPOSITIONS FOR METAL NANOPARTICLE TREATED SURFACES ACRYMED, INC. (US) 2008-11-19 EP disclosed
US-20070207335-A1 Methods and compositions for metal nanoparticle treated surfaces AVANOS MEDICAL SALES, LLC 2007-09-06 US disclosed
WO-2007095058-A2 METHODS AND COMPOSITIONS FOR METAL NANOPARTICLE TREATED SURFACES ACRYMED, INC. (US) 2007-08-23 WO disclosed