Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5031593 | 0.92 | ALDH1A1 (0.43) | ALDH1A1TP53CYP3A4 | |
| SCHEMBL4370786 | 0.92 | ALDH1A1 (0.43) | ALDH1A1TP53CYP3A4 | |
| SCHEMBL1685756 | 0.91 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2HCAR2TSHRTDP1 | |
| SCHEMBL607209 | 0.88 | TSHR (0.47) | ALDH1A1HCAR2TSHRTDP1 | |
| SCHEMBL9441621 | 0.88 | TSHR (0.47) | ALDH1A1HCAR2TSHRTDP1 | |
| SCHEMBL9453050 | 0.87 | ALDH1A1 (0.40) | ALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL1809474 | 0.87 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2TP53CYP3A4 | |
| SCHEMBL28547189 | 0.84 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL9129129 | 0.84 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL15772 | 0.83 | ALDH1A1 (0.59) | ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4764447-A | UNSATURATED ESTER MONOMER | RICOH CO., LTD. (JP) | 1988-08-16 | — | — | US | claimed |
| CN-108369376-A | The manufacturing method of photosensitive polymer combination, cured film, laminated body, touch panel component and cured film | 东丽株式会社 | 2018-08-03 | — | — | CN | disclosed |
| US-6541572-B2 | Copolymer containing oxirane graoups | ALCON MANUFACTURING, LTD. | 2003-04-01 | — | — | US | disclosed |
| US-20020019492-A1 | Method of making high refractive index ophthalmic device materials | NOVARTIS AG (CH) | 2002-02-14 | — | — | US | disclosed |
| US-4764447-A | UNSATURATED ESTER MONOMER | RICOH CO., LTD. (JP) | 1988-08-16 | — | — | US | disclosed |