SCHEMBL7214062

SCHEMBL7214062

Cc1ccc(C(=O)OF)c(F)c1F.[Ag]

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.49
HTT P42858 1/20 0.44
CES2 O00748 2/20 0.41
CES1 P23141 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.38
NTRK1 P04629 1/20 0.35
MYC P01106 1/20 0.33
HDAC1 Q13547 2/20 0.32
HDAC6 Q9UBN7 2/20 0.32
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC10 Q969S8 1/20 0.32
HDAC11 Q96DB2 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC9 Q9UKV0 1/20 0.32
HDAC5 Q9UQL6 1/20 0.32
HAAO P46952 1/20 0.32
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16672985 0.85 CES2 (0.52) HPGDHTTCES2CES1NPC1
SCHEMBL28830688 0.83 CES2 (0.50) HPGDCES2CES1
SCHEMBL1258800 0.82 HPGD (0.50) HPGDHTTCES2CES1MYC
SCHEMBL28830735 0.81 CES2 (0.48) HPGDCES2CES1
SCHEMBL14941129 0.79 TSHR (0.55) HPGDHTTTSHR
SCHEMBL27981046 0.78 HPGD (0.46) HPGDHTTCES2CES1L3MBTL1
SCHEMBL1578922 0.78 HPGD (0.46) HPGDHTTCES2CES1L3MBTL1
SCHEMBL27073671 0.78 HPGD (0.46) HPGDHTTCES2CES1L3MBTL1
SCHEMBL27541611 0.77 CES2 (0.45) HPGDCES2CES1HDAC4NPC1
SCHEMBL12327908 0.75 HPGD (0.55) HPGDHTTCES2CES1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1314725-A1 SULFONIUM SALT COMPOUND Wako Pure Chemical Industries, Ltd. (JP) 2003-05-28 EP disclosed