⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7214067 | 1.00 | — | — | |
| SCHEMBL7214061 | 1.00 | — | — | |
| SCHEMBL6935743 | 0.77 | — | — | |
| SCHEMBL8615914 | 0.74 | — | — | |
| SCHEMBL6850098 | 0.67 | — | — | |
| SCHEMBL7107969 | 0.67 | — | — | |
| SCHEMBL9824258 | 0.66 | — | — | |
| SCHEMBL122893 | 0.62 | — | — | |
| SCHEMBL17390965 | 0.60 | — | — | |
| SCHEMBL10561842 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61158986-A | — | — | None | — | — | JP | disclosed |
| EP-1044204-B1 | PROCESS FOR THE PREPARATION OF ALPHA-OXOLACTAMS | RES CORP TECHNOLOGIES INC (US) | 2003-06-04 | — | — | EP | disclosed |
| US-6255479-B1 | REACTING AN ALPHA-DIAZOLACTAM WITH AN EPOXIDE, IN THE PRESENCE OF A TRANSITION METAL CATALYST (OF RHODIUM, COPPER, OR RHENIUM), YIELDS ALPHA-OXOLACTAM | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2001-07-03 | — | — | US | disclosed |
| EP-1044204-A1 | PROCESS FOR THE PREPARATION OF ALPHA-OXOLACTAMS | Research Corporation Technologies, Inc (US) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999033837-A1 | PROCESS FOR THE PREPARATION OF α-OXOLACTAMS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1999-07-08 | — | — | WO | disclosed |
| JP-S61158986-A | PENAM DERIVATIVE AND PRODUCTION THEREOF | NIPPON REDARII KK | 1986-07-18 | — | — | JP | disclosed |
| EP-0013617-B1 | PENICILLIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING CERTAIN OF THESE COMPOUNDS | BEECHAM GROUP PLC (GB) | 1984-07-04 | — | — | EP | disclosed |
| EP-0013617-A1 | Penicillin derivatives, process for their preparation and pharmaceutical compositions containing certain of these compounds | BEECHAM GROUP PLC (GB) | 1980-07-23 | — | — | EP | disclosed |