⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935743 | 0.88 | — | — | |
| SCHEMBL6532238 | 0.73 | — | — | |
| SCHEMBL7214067 | 0.66 | — | — | |
| SCHEMBL7214064 | 0.66 | — | — | |
| SCHEMBL10824175 | 0.63 | — | — | |
| SCHEMBL7319780 | 0.63 | — | — | |
| SCHEMBL7387603 | 0.59 | PKM (0.31) | — | |
| SCHEMBL7387600 | 0.59 | PKM (0.31) | — | |
| SCHEMBL10436761 | 0.58 | — | — | |
| SCHEMBL10882211 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389064-A2 | Process for the preparation of 3-exomethylenecepham sulfoxide derivatives and intermediates therefor | GIST-BROCADES N.V. (NL) | 1990-09-26 | — | — | EP | claimed |
| JP-60187689-A | — | — | None | — | — | JP | disclosed |
| EP-0341694-A3 | METHOD FOR PRODUCTION OF 3-EXOMETHYLENECEPHAM DERIVATIVES | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1991-08-28 | — | — | EP | disclosed |
| EP-0389064-A2 | Process for the preparation of 3-exomethylenecepham sulfoxide derivatives and intermediates therefor | GIST-BROCADES N.V. (NL) | 1990-09-26 | — | — | EP | disclosed |
| EP-0341694-A2 | Method for production of 3-exomethylenecepham derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1989-11-15 | — | — | EP | disclosed |
| JP-S60187689-A | NANUFACTURE OF 3-EXO-METHYLENECEPHAM DERIVATIVE | OTSUKA CHEM CO LTD | 1985-09-25 | — | — | JP | disclosed |
| US-4042585-A | Process for preparation of 3-halomethylcephems | ELI LILLY AND COMPANY (US) | 1977-08-16 | — | — | US | disclosed |