Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6896883 | 0.90 | SIGMAR1 (0.40) | SIGMAR1HSD17B10TACR1MEN1KMT2A | |
| SCHEMBL7676098 | 0.90 | SIGMAR1 (0.40) | SIGMAR1HSD17B10TACR1MEN1KMT2A | |
| SCHEMBL7214805 | 0.87 | TACR1 (0.38) | SIGMAR1AVPR1AHSD17B10CHRM1HTR1A | |
| SCHEMBL27560030 | 0.81 | HSD17B10 (0.51) | AVPR1AHSD17B10CHRM1MEN1KMT2A | |
| SCHEMBL6895349 | 0.81 | HSD17B10 (0.51) | AVPR1AHSD17B10CHRM1MEN1KMT2A | |
| SCHEMBL6897368 | 0.81 | HSD17B10 (0.51) | AVPR1AHSD17B10CHRM1MEN1KMT2A | |
| SCHEMBL6732066 | 0.79 | CYP3A4 (0.41) | SIGMAR1MEN1KMT2A | |
| SCHEMBL6897654 | 0.78 | MC4R (0.37) | SIGMAR1AVPR1ATACR1MEN1KMT2A | |
| SCHEMBL6897620 | 0.78 | SIGMAR1 (0.37) | SIGMAR1HSD17B10TACR1MEN1KMT2A | |
| SCHEMBL6897866 | 0.77 | CYP3A4 (0.47) | AVPR1AHSD17B10CHRM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534499-B2 | For therapy of autoimmune disease | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2003-03-18 | — | — | US | disclosed |
| EP-1172359-A1 | N-SUBSTITUTED-N'-SUBSTITUTED UREA DERIVATIVE AND USE THEREOF AS TNF-$g(a) PRODUCTION INHIBITOR | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-01-16 | — | — | EP | disclosed |