Methacrylic Acid

Methacrylic Acid

SCHEMBL7214459

C=C(C)C(=O)O.CC(O)CCO.CCCOCCC

nearest known ligand 0.41

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Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.36
THRB P10828 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 4/20 0.32
KDM4E B2RXH2 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,3-Butanediol SCHEMBL4329578 0.90 HSD17B10 (0.47) HSD17B10TDP1THRBMEN1KMT2A
Methacrylic Acid SCHEMBL7219389 0.88 HSD17B10 (0.45) HSD17B10TDP1THRBMEN1KMT2A
Methacrylic Acid SCHEMBL8440366 0.86 TGFBR1 (0.33) TDP1TSHRALDH1A1
Methacrylic Acid SCHEMBL18140418 0.86 TGFBR1 (0.35) TDP1TSHRALDH1A1ALOX15
Methacrylic Acid SCHEMBL1042271 0.86 TGFBR1 (0.35) TDP1TSHRALDH1A1ALOX15
Methacrylic Acid SCHEMBL18140496 0.86 TGFBR1 (0.35) TDP1TSHRALDH1A1ALOX15
Methacrylic Acid SCHEMBL732038 0.86 TGFBR1 (0.35) TDP1TSHRALDH1A1ALOX15
Methacrylic Acid SCHEMBL9779417 0.86 TGFBR1 (0.35) TDP1TSHRALDH1A1ALOX15
Methacrylic Acid SCHEMBL24964 0.86 TGFBR1 (0.35) TDP1TSHRALDH1A1ALOX15
Methacrylic Acid SCHEMBL18139477 0.86 TGFBR1 (0.35) TDP1TSHRALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6624236-B1 Sol-gel-condensable cyclosiloxane(meth) acrylates; dentistry 3M ESPE AG (DE) 2003-09-23 US disclosed
EP-1141094-B1 CYCLOSILOXANE-BASED CROSS-LINKABLE MONOMERS, PRODUCTION THEREOF AND USE THEREOF IN POLYMERISABLE MATERIALS 3M ESPE AG (DE) 2002-07-24 EP disclosed