Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.65 |
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.59 |
| ▸ | PARP15 | Q460N3 | 6/20 | 0.59 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657957 | 0.96 | NFE2L2 (0.69) | NFE2L2PARP10PARP15PARP2HPGD | |
| SCHEMBL745672 | 0.94 | NFE2L2 (0.66) | NFE2L2PARP10PARP15PARP2TDP1 | |
| SCHEMBL2563096 | 0.91 | PARP10 (0.62) | NFE2L2PARP10PARP15PARP2TDP1 | |
| SCHEMBL2565996 | 0.87 | PARP15 (0.59) | NFE2L2PARP10PARP15PARP2TDP1 | |
| SCHEMBL81903 | 0.81 | PARP15 (0.58) | PARP10PARP15PARP2TDP1FFAR1 | |
| SCHEMBL13439690 | 0.81 | FFAR1 (0.56) | NFE2L2PARP10PARP15PARP2TDP1 | |
| SCHEMBL8178695 | 0.80 | PARP10 (0.57) | NFE2L2PARP10PARP15PARP2TSHR | |
| SCHEMBL11164865 | 0.79 | PARP15 (0.57) | PARP10PARP15PARP2TDP1FFAR1 | |
| SCHEMBL20969565 | 0.79 | PARP10 (0.56) | PARP10PARP15PARP2FFAR1 | |
| SCHEMBL7214458 | 0.79 | PARP10 (0.56) | NFE2L2PARP10PARP15PARP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576766-B1 | Competitive binding of phosphotyrosine-containing protein; veterinary medicine | ARIAD PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |