Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 3/20 | 0.46 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.41 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | RNMT | O43148 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.34 |
| ▸ | ABL1 | P00519 | 6/20 | 0.33 |
| ▸ | EGFR | P00533 | 5/20 | 0.33 |
| ▸ | ABL2 | P42684 | 4/20 | 0.33 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | TEK | Q02763 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 4/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6880733 | 0.78 | ADK (0.44) | ADKDOT1LPRMT5PRMT3DNMT1 | |
| SCHEMBL6875297 | 0.71 | ADK (0.55) | ADKDOT1LPRMT5PRMT3DNMT1 | |
| SCHEMBL6876234 | 0.65 | ADK (0.73) | ADKDOT1LPRMT5PRMT3DNMT1 | |
| SCHEMBL6879012 | 0.65 | ADK (0.73) | ADKDOT1LPRMT5PRMT3DNMT1 | |
| SCHEMBL6868897 | 0.65 | ADK (0.43) | ADKDOT1LPRMT5PRMT3DNMT1 | |
| SCHEMBL31022850 | 0.65 | ADK (0.41) | ADKDOT1LPRMT5PRMT3DNMT1 | |
| SCHEMBL27195436 | 0.65 | ADK (0.41) | ADKDOT1LPRMT5PRMT3DNMT1 | |
| SCHEMBL6877410 | 0.64 | ADK (1.00) | ADKDOT1LPRMT5PRMT3DNMT1 | |
| SCHEMBL6877858 | 0.63 | ADK (0.69) | ADKDOT1LPRMT5PRMT3DNMT1 | |
| SCHEMBL6877859 | 0.63 | ADK (0.69) | ADKDOT1LPRMT5PRMT3DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212326-A4 | PYRROLO 2,3-d]PYRIMIDINE NUCLEOSIDE ANALOGS | ICN PHARMACEUTICALS (US) | 2003-08-20 | — | — | EP | disclosed |
| EP-1212326-A1 | PYRROLO 2,3-d]PYRIMIDINE NUCLEOSIDE ANALOGS | ICN Pharmaceuticals, Inc. (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001027114-A1 | PYRROLO[2,3-d]PYRIMIDINE NUCLEOSIDE ANALOGS | ICN PHARMACEUTICALS, INC. (US) | 2001-04-19 | — | — | WO | disclosed |