Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 13/20 | 0.54 |
| ▸ | FNTB | P49356 | 13/20 | 0.54 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6010464 | 0.82 | FNTA (0.60) | FNTAFNTBPGGT1BMEN1KMT2A | |
| SCHEMBL7762145 | 0.77 | FNTA (0.58) | FNTAFNTBPGGT1BMEN1KMT2A | |
| SCHEMBL11947180 | 0.72 | FNTA (0.59) | FNTAFNTBPGGT1BMEN1KMT2A | |
| SCHEMBL5733786 | 0.70 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL13186537 | 0.70 | FNTA (1.00) | FNTAFNTB | |
| Hydrochloric Acid SCHEMBL6010278 | 0.69 | FNTA (0.90) | FNTAFNTBPGGT1B | |
| Water SCHEMBL7207857 | 0.68 | FNTA (0.67) | FNTAFNTBPGGT1B | |
| SCHEMBL5778239 | 0.68 | FNTA (0.68) | FNTAFNTBPGGT1BIDO1 | |
| SCHEMBL4562526 | 0.68 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL4562525 | 0.68 | FNTA (1.00) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322644-A1 | FARNESYL TRANSFERASE INHIBITING 6-HETEROCYCLYLMETHYL QUINOLINONE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002024687-A1 | FARNESYL TRANSFERASE INHIBITING 6-HETEROCYCLYLMETHYL QUINOLINONE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-03-28 | — | — | WO | disclosed |