Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 15/20 | 0.58 |
| ▸ | FNTB | P49356 | 15/20 | 0.58 |
| ▸ | PGGT1B | P53609 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587313 | 0.88 | FNTA (0.49) | FNTAFNTBPGGT1B | |
| SCHEMBL7707732 | 0.84 | FNTA (0.76) | FNTAFNTBPGGT1B | |
| SCHEMBL6010464 | 0.84 | FNTA (0.60) | FNTAFNTBPGGT1BMEN1KMT2A | |
| SCHEMBL7214749 | 0.77 | FNTA (0.54) | FNTAFNTBPGGT1BMEN1KMT2A | |
| SCHEMBL8181649 | 0.75 | FNTA (0.67) | FNTAFNTBPGGT1B | |
| SCHEMBL11947180 | 0.73 | FNTA (0.59) | FNTAFNTBPGGT1BMEN1KMT2A | |
| SCHEMBL4562525 | 0.73 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL4562526 | 0.73 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL13529456 | 0.73 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL4156125 | 0.72 | FNTA (0.85) | FNTAFNTBMEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1094810-A1 | USE OF PRENYLTRANSFERASE INHIBITORS FOR PREPARING A MEDICINE FOR TREATING PATHOLOGIES RESULTING FROM HETEROTRIMERIC G PROTEIN MEMBRANE FIXATION | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000002558-A1 | USE OF PRENYLTRANSFERASE INHIBITORS FOR PREPARING A MEDICINE FOR TREATING PATHOLOGIES RESULTING FROM HETEROTRIMERIC G PROTEIN MEMBRANE FIXATION | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-01-20 | — | — | WO | disclosed |