Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026582 | 0.87 | ALDH1A1 (0.33) | ALDH1A1HSD17B10MEN1LMNAMAPT | |
| SCHEMBL29569948 | 0.76 | ALDH1A1 (0.35) | ALDH1A1HSD17B10MEN1LMNAMAPT | |
| SCHEMBL29422894 | 0.76 | ALDH1A1 (0.35) | ALDH1A1HSD17B10MEN1LMNAMAPT | |
| SCHEMBL29385734 | 0.76 | CES1 (0.45) | ALDH1A1HSD17B10MEN1LMNAMAPT | |
| SCHEMBL5894113 | 0.76 | ALDH1A1 (0.35) | ALDH1A1HSD17B10MEN1LMNAMAPT | |
| SCHEMBL2926382 | 0.76 | ALDH1A1 (0.35) | ALDH1A1HSD17B10MEN1LMNAMAPT | |
| SCHEMBL2324920 | 0.76 | ALDH1A1 (0.35) | ALDH1A1HSD17B10MEN1LMNAMAPT | |
| SCHEMBL2926757 | 0.76 | ALDH1A1 (0.35) | ALDH1A1HSD17B10MEN1LMNAMAPT | |
| SCHEMBL219752 | 0.76 | TSHR (0.36) | ALDH1A1HSD17B10MEN1LMNAMAPT | |
| SCHEMBL1941287 | 0.76 | ALDH1A1 (0.40) | ALDH1A1HSD17B10MEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610875-B1 | Forming bidentate ligands ofr assymetric catalysts; bromina-ting diaryldiol; esterifying with sulfonic acid; substituting cyano for bromine groups; coupling with a dicyclophosphine | RHODIA CHIMIE (FR) | 2003-08-26 | — | — | US | disclosed |