Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 2/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.58 |
| ▸ | CTSV | O60911 | 3/20 | 0.56 |
| ▸ | CTSL | P07711 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3138320 | 0.91 | CTSV (0.57) | SRD5A1SRD5A2CTSVCTSLHPGD | |
| SCHEMBL4728946 | 0.91 | CTSV (0.57) | SRD5A1SRD5A2CTSVCTSLHPGD | |
| SCHEMBL4982256 | 0.86 | SRD5A1 (0.49) | SRD5A1SRD5A2CTSVCTSLHPGD | |
| SCHEMBL28017860 | 0.82 | SRD5A1 (0.58) | SRD5A1SRD5A2CTSVCTSLHPGD | |
| SCHEMBL28102561 | 0.82 | SRD5A1 (0.58) | SRD5A1SRD5A2CTSVCTSLHPGD | |
| SCHEMBL28018441 | 0.82 | SRD5A1 (0.58) | SRD5A1SRD5A2CTSVCTSLHPGD | |
| SCHEMBL159448 | 0.82 | HTT (0.55) | SRD5A1SRD5A2CTSVCTSLHPGD | |
| SCHEMBL874091 | 0.82 | HTT (0.55) | SRD5A1SRD5A2CTSVCTSLHPGD | |
| SCHEMBL4469125 | 0.82 | SMN1; SMN2 (0.52) | SRD5A1SRD5A2CTSVCTSLHPGD | |
| SCHEMBL340527 | 0.82 | SMN1; SMN2 (0.52) | SRD5A1SRD5A2CTSVCTSLHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345889-A1 | METHOD FOR THE REGIOSELECTIVE PREPARATION OF SUBSTITUTED BENZO G]QUINOLINE-3-CARBONITRILES AND BENZO G]QUINAZOLINES | Wyeth (US) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002053528-A1 | METHOD FOR THE REGIOSELECTIVE PREPARATION OF SUBSTITUTED BENZO[G]QUINOLINE-3-CARBONITRILES AND BENZO[G]QUINAZOLINES | WYETH (US) | 2002-07-11 | — | — | WO | disclosed |