Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7214985 | 1.00 | KDM4E (0.40) | KDM4EPTGDR2RIPK1RORCAPEX1 | |
| SCHEMBL7214972 | 1.00 | KDM4E (0.40) | KDM4EPTGDR2RIPK1RORCAPEX1 | |
| SCHEMBL7216094 | 0.89 | KDM4E (0.43) | KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7216082 | 0.89 | KDM4E (0.43) | KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7216088 | 0.89 | KDM4E (0.43) | KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7219640 | 0.75 | F2 (0.37) | — | |
| SCHEMBL7219637 | 0.75 | F2 (0.37) | — | |
| SCHEMBL7219642 | 0.75 | F2 (0.37) | — | |
| SCHEMBL7219520 | 0.73 | TSHR (0.46) | KDM4E | |
| SCHEMBL7219522 | 0.73 | TSHR (0.46) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610692-B1 | Anticoagulants | MERCK & CO., INC. | 2003-08-26 | — | — | US | disclosed |