Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215106 | 1.00 | HIF1A (0.47) | HIF1ATP53HTTMRGPRX4OPRL1 | |
| SCHEMBL8368525 | 0.89 | HIF1A (0.45) | HIF1AMRGPRX4SCN9A | |
| SCHEMBL8368530 | 0.89 | HIF1A (0.45) | HIF1AMRGPRX4SCN9A | |
| SCHEMBL829036 | 0.86 | HIF1A (0.49) | HIF1ATP53HTTMRGPRX4SCN9A | |
| SCHEMBL829037 | 0.86 | HIF1A (0.49) | HIF1ATP53HTTMRGPRX4SCN9A | |
| SCHEMBL8341973 | 0.85 | HIF1A (0.42) | HIF1ATP53HTTMRGPRX4OPRL1 | |
| SCHEMBL8341971 | 0.85 | HIF1A (0.42) | HIF1ATP53HTTMRGPRX4OPRL1 | |
| SCHEMBL8369597 | 0.84 | HIF1A (0.51) | HIF1ATP53HTTMRGPRX4CLCN2 | |
| SCHEMBL8369599 | 0.84 | HIF1A (0.51) | HIF1ATP53HTTMRGPRX4CLCN2 | |
| SCHEMBL8337628 | 0.83 | HIF1A (0.45) | HIF1ATP53HTTMRGPRX4SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6559170-B1 | Compounds are useful as fungicides in plants | DOW AGROSCIENCE LLC | 2003-05-06 | — | — | US | disclosed |
| EP-1237870-A1 | PYRIDINE DERIVATIVES HAVING FUNGICIDAL ACTIVITY AND PROCESSES TO PRODUCE AND USE THE SAME | Dow AgroSciences LLC (US) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001044196-A1 | PYRIDINE DERIVATIVES HAVING FUNGICIDAL ACTIVITY AND PROCESSES TO PRODUCE AND USE THE SAME | DOW AGROSCIENCES, LLC (US) | 2001-06-21 | — | — | WO | disclosed |