Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL829037 | 1.00 | HIF1A (0.49) | HIF1AMRGPRX4SGMS2SCN9APSMB5 | |
| SCHEMBL8343054 | 0.89 | HIF1A (0.46) | HIF1AMRGPRX4SCN9ALMNATP53 | |
| SCHEMBL8337628 | 0.89 | HIF1A (0.45) | HIF1AMRGPRX4SCN9ATP53HTT | |
| SCHEMBL8337626 | 0.89 | HIF1A (0.45) | HIF1AMRGPRX4SCN9ATP53HTT | |
| SCHEMBL8343050 | 0.89 | HIF1A (0.46) | HIF1AMRGPRX4SCN9ALMNATP53 | |
| SCHEMBL829098 | 0.88 | HIF1A (0.46) | HIF1AMRGPRX4SGMS2POLB | |
| SCHEMBL829099 | 0.88 | HIF1A (0.46) | HIF1AMRGPRX4SGMS2POLB | |
| SCHEMBL8105497 | 0.88 | HIF1A (0.46) | HIF1AMRGPRX4SGMS2POLB | |
| SCHEMBL8370602 | 0.88 | HIF1A (0.50) | HIF1AMRGPRX4SCN9ALMNAPOLB | |
| SCHEMBL7521316 | 0.88 | HIF1A (0.45) | HIF1AMRGPRX4SCN9ATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143275-B2 | Use of triazolopyrimidine derivatives as microbicides | LANXESS DEUTSCHLAND GMBH (DE) | 2012-03-27 | — | — | US | disclosed |
| US-20110098279-A1 | USE OF TRIAZOLOPYRIMIDINE DERIVATIVES AS MICROBICIDES | LANXESS DEUTSCHLAND GMBH (DE) | 2011-04-28 | — | — | US | disclosed |
| US-7888371-B2 | For protecting engineered wood, timber, or plastic from phytopathogenic fungi | LANXESS DEUTSCHLAND GMBH (DE) | 2011-02-15 | — | — | US | disclosed |
| EP-1395117-B2 | USE OF TRIAZOLOPYRIMIDINE DERIVATIVES AS MICROBICIDES IN THE PROTECTION OF MATERIALS | LANXESS DEUTSCHLAND GMBH (DE) | 2009-09-30 | — | — | EP | disclosed |
| US-7084137-B2 | Thiazines and thiazoles as agents for protecting materials | BAYER AKTIENGESELLSCHAFT (DE) | 2006-08-01 | — | — | US | disclosed |
| EP-1395117-B1 | USE OF TRIAZOLOPYRIMIDINE DERIVATIVES AS MICROBICIDES IN THE PROTECTION OF MATERIALS | LANXESS DEUTSCHLAND GMBH (DE) | 2006-07-26 | — | — | EP | disclosed |
| US-6835842-B2 | Microbiocides; bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 2004-12-28 | — | — | US | disclosed |
| US-20040204405-A1 | Thiazines and thiazoles as agents for protecting materials | LANXESS DEUTSCHLAND GMBH (DE) | 2004-10-14 | — | — | US | disclosed |
| EP-1437940-A1 | THIAZINES AND THIAZOLES FOR USE AS MATERIAL PROTECTIVE AGENTS | Bayer Chemicals AG (DE) | 2004-07-21 | — | — | EP | disclosed |
| EP-1395117-A1 | USE OF TRIAZOLOPYRIMIDINE DERIVATIVES AS MICROBICIDES IN THE PROTECTION OF MATERIALS | Bayer Chemicals AG (DE) | 2004-03-10 | — | — | EP | disclosed |
| EP-0975611-A1 | 3-ALKOXY ISOTHIAZOLES | BAYER AG (DE) | 2000-02-02 | — | — | EP | disclosed |
| WO-1999062911-A1 | PYRIDODITHIAZINE DIOXIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-09 | — | — | WO | disclosed |
| EP-0950055-A1 | ARYLTHIO-DITHIAZINDIOXIDES AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1999-10-20 | — | — | EP | disclosed |
| EP-0617011-B1 | Process for producing alkoxyiminoacetamide compounds | SHIONOGI & CO (JP) | 1999-01-20 | — | — | EP | disclosed |
| WO-1998045258-A1 | 1-CYANO-2-ALKYLTHIO-2-ARYLTHIOETHENES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-15 | — | — | WO | disclosed |
| WO-1998042689-A1 | 3-ALKOXY ISOTHIAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-01 | — | — | WO | disclosed |
| WO-1998039969-A1 | ALGICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-17 | — | — | WO | disclosed |
| WO-1998029400-A1 | ARYLTHIO-DITHIAZINDIOXIDES AND THEIR USE AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-09 | — | — | WO | disclosed |
| US-5506358-A | USEFUL AS AGRICULTURAL FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0617011-A2 | Process for producing alkoxyiminoacetamide compounds | SHIONOGI & CO., LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204405-A1 | Thiazines and thiazoles as agents for protecting materials | POT1, NAT1, GPX1 | HIF1A 2331/4885MRGPRX4 2783/4885SGMS2 3897/4885 |
| US-20110098279-A1 | USE OF TRIAZOLOPYRIMIDINE DERIVATIVES AS MICROBICIDES | ARG2, MSR1, TK2 | HIF1A 1989/4885MRGPRX4 22/4885SGMS2 1753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.