SCHEMBL7215124

SCHEMBL7215124

C=C(C)C(=O)OC(C)Oc1ccccc1C(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.47
MAPT P10636 6/20 0.42
MAPK1 P28482 2/20 0.42
ABCB1 P08183 5/20 0.41
IRAK4 Q9NWZ3 1/20 0.40
AKR1C3 P42330 1/20 0.39
KDM4E B2RXH2 3/20 0.39
HSD17B10 Q99714 3/20 0.39
HPGD P15428 2/20 0.39
ALDH1A1 P00352 2/20 0.39
ESR1 P03372 1/20 0.39
ITGB3 P05106 1/20 0.39
ITGA2B P08514 1/20 0.39
HMGB1 P09429 1/20 0.39
TSHR P16473 1/20 0.39
GGT1 P19440 1/20 0.39
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
BLM P54132 1/20 0.39
NAPRT Q6XQN6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8989321 0.90 MAPT (0.43) ELANEMAPTMAPK1ABCB1AKR1C3
SCHEMBL28107067 0.85 MAPT (0.56) ELANEMAPTMAPK1KDM4EHSD17B10
SCHEMBL10764874 0.84 KMT2A (0.42) ELANEMAPTIRAK4KDM4EHSD17B10
SCHEMBL4410811 0.82 ELANE (0.40) ELANEMAPTMAPK1ABCB1IRAK4
SCHEMBL721897 0.81 ELANE (0.46) ELANEMAPTMAPK1ABCB1IRAK4
SCHEMBL474811 0.81 ELANE (0.64) ELANEMAPTMAPK1ABCB1AKR1C3
SCHEMBL29670258 0.81 ELANE (0.64) ELANEMAPTMAPK1ABCB1AKR1C3
SCHEMBL2403088 0.81 ELANE (0.64) ELANEMAPTMAPK1ABCB1HPGD
SCHEMBL17065868 0.81 ELANE (0.48) ELANEMAPTMAPK1ABCB1IRAK4
SCHEMBL2419965 0.80 LMNA (0.58) ELANEMAPTMAPK1KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105164187-B Production includes the method for the laminates of the adhesive sheet of solidification 3M创新有限公司 2017-08-11 CN disclosed
US-6620362-B1 Copolymerizing diol and naphthalenedicarboxylic acid NAN YA PLASTICS CORPORATION (TW) 2003-09-16 US disclosed