Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29423328 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL6359411 | 1.00 | — | — | |
| SCHEMBL28822656 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL7847798 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL11338439 | 0.71 | — | — | |
| SCHEMBL29795443 | 0.71 | — | — | |
| SCHEMBL4049251 | 0.71 | — | — | |
| SCHEMBL4403656 | 0.71 | — | — | |
| SCHEMBL9821880 | 0.71 | — | — | |
| Ammonia Solution, Strong SCHEMBL9800883 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6624143-B1 | Antibiotics of the amphomycin type are characterized by the exocyclic amino acid aspartic acid (Asp, cyclic oligopeptides Antimicrobial Agents and Chemotherapy | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-09-23 | — | — | US | disclosed |
| EP-1068223-B1 | CALCIUM SALTS OF LIPOPEPTIDE ANTIBIOTICS, METHOD FOR PRODUCING SAME AND THEIR USE | AVENTIS PHARMA GMBH (DE) | 2002-09-04 | — | — | EP | disclosed |
| EP-1068223-A1 | CALCIUM SALTS OF LIPOPEPTIDE ANTIBIOTICS, METHOD FOR PRODUCING SAME AND THEIR USE | Aventis Pharma Deutschland GmbH (DE) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999043700-A1 | CALCIUM SALTS OF LIPOPEPTIDE ANTIBIOTICS, METHOD FOR PRODUCING SAME AND THEIR USE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-09-02 | — | — | WO | disclosed |