Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 12/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 11/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 11/20 | 0.42 |
| ▸ | TLR4 | O00206 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834381 | 1.00 | GNAO1 (0.42) | GNAO1GNAI3GNAI1TLR4CYP1A2 | |
| SCHEMBL26805 | 0.85 | — | — | |
| SCHEMBL6697654 | 0.85 | TLR4 (0.42) | TLR4CYP1A2CYP2C9 | |
| SCHEMBL5836344 | 0.85 | TLR4 (0.42) | TLR4CYP1A2CYP2C9 | |
| SCHEMBL5836340 | 0.85 | TLR4 (0.42) | TLR4CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL25188607 | 0.83 | GNAO1 (0.52) | GNAO1GNAI3GNAI1CYP1A2HRH3 | |
| Ammonia Solution, Strong SCHEMBL27635439 | 0.83 | GNAO1 (0.47) | GNAO1GNAI3GNAI1CYP1A2HRH3 | |
| SCHEMBL11019071 | 0.83 | TLR4 (0.41) | TLR4CYP1A2CYP2C9 | |
| SCHEMBL8217513 | 0.83 | TLR4 (0.41) | TLR4CYP1A2CYP2C9 | |
| SCHEMBL11019067 | 0.83 | TLR4 (0.41) | TLR4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |
| US-10034886-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2018-07-31 | — | — | US | disclosed |
| EP-2484744-B1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORP (JP) | 2018-04-25 | — | — | EP | disclosed |
| US-20180021346-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2018-01-25 | — | — | US | disclosed |
| US-9795613-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-10-24 | — | — | US | disclosed |
| EP-3230276-A1 | GLP-1 RECEPTOR MODULATORS | Celgene International II Sarl (CH) | 2017-10-18 | — | — | EP | disclosed |
| US-20160228450-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2016-08-11 | — | — | US | disclosed |
| WO-2016094729-A1 | GLP-1 RECEPTOR MODULATORS | CELGENE INTERNATIONAL II SARL (CH) | 2016-06-16 | — | — | WO | disclosed |
| US-6576303-B1 | Negative and absolutely large Delta set- membership value | CHISSO CORPORATION (JP) | 2003-06-10 | — | — | US | disclosed |
| EP-1072593-A1 | LIQUID CRYSTALLINE COMPOUND HAVING PIPERIDINE RING, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 2001-01-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160228450-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | GNAO1 710/4885GNAI3 752/4885GNAI1 522/4885 |
| US-20180021346-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | GNAO1 710/4885GNAI3 752/4885GNAI1 522/4885 |
| US-10034886-B2 | GLP-1 receptor modulators | GLP1R, GIPR, GCGR | GNAO1 769/4885GNAI3 726/4885GNAI1 485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.