SCHEMBL7215282

SCHEMBL7215282

COC(=O)CC[C@@H](NC(=O)OCc1ccccc1)C(=O)OC(C)(C)C

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SYK P43405 1/20 0.54
CTSK P43235 6/20 0.51
CTSL P07711 3/20 0.50
CTSS P25774 3/20 0.50
CTSB P07858 2/20 0.50
ALDH1A1 P00352 1/20 0.49
ALOX15 P16050 1/20 0.49
PPARA Q07869 2/20 0.48
KYNU Q16719 1/20 0.48
SIRT2 Q8IXJ6 1/20 0.48
SIRT1 Q96EB6 1/20 0.48
SIRT3 Q9NTG7 1/20 0.48
CASP1 P29466 2/20 0.47
PPARG P37231 1/20 0.47
BCHE P06276 1/20 0.46
ACHE P22303 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2578490 1.00 SYK (0.54) SYKCTSKCTSLCTSSCTSB
SCHEMBL2578492 1.00 SYK (0.54) SYKCTSKCTSLCTSSCTSB
SCHEMBL9819558 0.94 SYK (0.55) SYKCTSKCTSLCTSSCTSB
SCHEMBL13570900 0.94 SYK (0.55) SYKCTSKCTSLCTSSCTSB
SCHEMBL13570899 0.94 SYK (0.55) SYKCTSKCTSLCTSSCTSB
SCHEMBL12888369 0.91 PPARA (0.54) SYKCTSKCTSLCTSSCTSB
SCHEMBL21541316 0.91 KYNU (0.54) SYKCTSKCTSLCTSSCTSB
SCHEMBL27688789 0.91 PPARA (0.54) SYKCTSKCTSLCTSSCTSB
SCHEMBL20346744 0.91 KYNU (0.54) SYKCTSKCTSLCTSSCTSB
SCHEMBL15941011 0.91 PPARA (0.54) SYKCTSKCTSLCTSSCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025224463-A1 DESMURAMYLPEPTIDE ANALOGUE MONOESTER Imhotex Limited (GB) 2025-10-30 WO disclosed
WO-2024224089-A1 DESMURAMYLPEPTIDE MONOESTERS AS NOD2 AGONISTS AND USE THEREOF Imhotex Limited (GB) 2024-10-31 WO disclosed
US-6599890-B1 Inhibitors of matrix metalloproteinases or the production of tumor necrosis factor PFIZER INC 2003-07-29 US disclosed
EP-0960098-A1 ARYLSULFONYL HYDROXAMIC ACID DERIVATIVES PFIZER INC. (US) 1999-12-01 EP disclosed
WO-1998034918-A1 ARYLSULFONYL HYDROXAMIC ACID DERIVATIVES PFIZER INC. (US) 1998-08-13 WO disclosed