Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 10/20 | 0.62 |
| ▸ | MAPK12 | P53778 | 10/20 | 0.62 |
| ▸ | MAPK11 | Q15759 | 10/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.62 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.54 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.53 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.53 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.53 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.52 |
| ▸ | RAF1 | P04049 | 3/20 | 0.52 |
| ▸ | GCGR | P47871 | 2/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | FRK | P42685 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.46 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5769910 | 1.00 | MAPK13 (0.62) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5770995 | 0.86 | SOAT1 (0.68) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL8104857 | 0.84 | MAPK13 (0.73) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5772456 | 0.84 | MAPK13 (0.65) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5768771 | 0.84 | MAPK13 (0.65) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5769076 | 0.82 | MAPK14 (0.64) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5769272 | 0.82 | MAPK13 (0.61) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5771323 | 0.82 | MAPK13 (0.61) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5797741 | 0.81 | SOAT1 (0.70) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5769642 | 0.81 | MAPK13 (0.74) | MAPK13MAPK12MAPK11MAPK14SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602877-B1 | Imidazolyl-cyclic acetals | AVENTIS PHARMA LIMITED (GB) | 2003-08-05 | — | — | US | disclosed |