Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 8/20 | 0.73 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.73 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.73 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.73 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.51 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.51 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.50 |
| ▸ | RAF1 | P04049 | 3/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | FRK | P42685 | 1/20 | 0.44 |
| ▸ | GCGR | P47871 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.44 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6808760 | 0.86 | MAPK13 (0.64) | MAPK13MAPK12MAPK11MAPK14CSNK1A1 | |
| SCHEMBL5770995 | 0.85 | SOAT1 (0.68) | MAPK13MAPK12MAPK11MAPK14CSNK1A1 | |
| SCHEMBL20555598 | 0.84 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14CSNK1A1 | |
| SCHEMBL18797648 | 0.84 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14CSNK1A1 | |
| SCHEMBL5770288 | 0.84 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14CSNK1A1 | |
| SCHEMBL7215418 | 0.84 | MAPK13 (0.62) | MAPK13MAPK12MAPK11MAPK14CSNK1A1 | |
| SCHEMBL5769910 | 0.84 | MAPK13 (0.62) | MAPK13MAPK12MAPK11MAPK14CSNK1A1 | |
| Hydrochloric Acid SCHEMBL5768856 | 0.83 | MAPK13 (0.97) | MAPK13MAPK12MAPK11MAPK14CSNK1A1 | |
| Bromide SCHEMBL5770111 | 0.83 | MAPK13 (0.97) | MAPK13MAPK12MAPK11MAPK14CSNK1A1 | |
| SCHEMBL5772456 | 0.83 | MAPK13 (0.65) | MAPK13MAPK12MAPK11MAPK14CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988301-A1 | IMIDAZOLYL-CYCLIC ACETALS | RHONE-POULENC RORER LIMITED (GB) | 2000-03-29 | — | — | EP | claimed |
| WO-1998056788-A1 | IMIDAZOLYL-CYCLIC ACETALS | RHONE-POULENC RORER LIMITED (GB) | 1998-12-17 | — | — | WO | claimed |
| EP-0988301-A1 | IMIDAZOLYL-CYCLIC ACETALS | RHONE-POULENC RORER LIMITED (GB) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998056788-A1 | IMIDAZOLYL-CYCLIC ACETALS | RHONE-POULENC RORER LIMITED (GB) | 1998-12-17 | — | — | WO | disclosed |