Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | CCR1 | P32246 | 3/20 | 0.53 |
| ▸ | CCR5 | P51681 | 3/20 | 0.53 |
| ▸ | CCR8 | P51685 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29363753 | 0.89 | KDM4E (0.43) | KDM4ESMN1; SMN2LMNATP53HTT | |
| SCHEMBL15190588 | 0.89 | KDM4E (0.43) | KDM4ESMN1; SMN2LMNATP53HTT | |
| SCHEMBL15198744 | 0.88 | KDM4E (0.42) | KDM4ESMN1; SMN2LMNATP53HTT | |
| SCHEMBL15190581 | 0.88 | KDM4E (0.42) | KDM4ESMN1; SMN2LMNATP53HTT | |
| SCHEMBL29363210 | 0.88 | KDM4E (0.42) | KDM4ESMN1; SMN2LMNATP53HTT | |
| SCHEMBL828964 | 0.87 | KDM4E (0.47) | KDM4ESMN1; SMN2LMNATP53HTT | |
| SCHEMBL835218 | 0.87 | KDM4E (0.47) | KDM4ESMN1; SMN2LMNATP53HTT | |
| SCHEMBL835206 | 0.87 | L3MBTL1 (0.49) | KDM4ESMN1; SMN2LMNATP53HTT | |
| SCHEMBL834539 | 0.85 | KDM4E (0.46) | KDM4ESMN1; SMN2LMNATP53HTT | |
| SCHEMBL834325 | 0.85 | KDM4E (0.46) | KDM4ESMN1; SMN2LMNATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |