Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.53 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215467 | 0.94 | NR1H4 (0.67) | NR1H4KMT2AMEN1ITGA4ITGB1 | |
| SCHEMBL6940065 | 0.88 | ITGB1 (0.57) | NR1H4KMT2AMEN1ITGA4ITGB1 | |
| SCHEMBL7031467 | 0.83 | NR1H4 (0.90) | NR1H4KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL13692888 | 0.80 | NR1H4 (0.67) | NR1H4KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL1333051 | 0.79 | NR1H4 (0.62) | NR1H4KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL3522987 | 0.79 | NR1H4 (0.69) | NR1H4KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL2414237 | 0.78 | MEN1 (0.66) | NR1H4KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL13538746 | 0.78 | NR1H4 (0.58) | NR1H4KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL6041621 | 0.78 | NR1H4 (1.00) | NR1H4KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL134782 | 0.77 | MEN1 (0.64) | NR1H4KMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6559179-B1 | Tinvention relates to the use of compounds as inhibitors of the fatty acid synthase FabH. | SMITHKLINE BEECHAM CORPORATION | 2003-05-06 | — | — | US | disclosed |