Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1396453 | 0.88 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL27829147 | 0.79 | CA12 (0.39) | SIGMAR1 | |
| SCHEMBL14735285 | 0.74 | SIGMAR1 (0.44) | SIGMAR1 | |
| SCHEMBL4514697 | 0.72 | — | — | |
| SCHEMBL13446778 | 0.72 | — | — | |
| SCHEMBL5715278 | 0.70 | — | — | |
| SCHEMBL26780 | 0.67 | — | — | |
| SCHEMBL28592280 | 0.67 | TSHR (0.43) | — | |
| SCHEMBL25663957 | 0.67 | PIK3CD (0.42) | SIGMAR1 | |
| SCHEMBL25663958 | 0.67 | PIK3CD (0.42) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084129-B1 | CYCLIC BOROPROLINE COMPOUNDS | POINT THERAPEUTICS INC (US) | 2003-01-22 | — | — | EP | disclosed |
| US-6355614-B1 | Cyclic boroproline compounds | POINT THERAPEUTICS | 2002-03-12 | — | — | US | disclosed |
| EP-1084129-A1 | CYCLIC BOROPROLINE COMPOUNDS | Point Therapeutics, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999062914-A1 | CYCLIC BOROPROLINE COMPOUNDS | POINT THERAPEUTICS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |