Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.43 |
| ▸ | F2 | P00734 | 6/20 | 0.39 |
| ▸ | PROC | P04070 | 4/20 | 0.39 |
| ▸ | PLG | P00747 | 3/20 | 0.39 |
| ▸ | PLAT | P00750 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6221898 | 0.90 | F10 (0.52) | F10F2ROCK1ROCK2KCNH2 | |
| SCHEMBL7214419 | 0.86 | MET (0.41) | F10F2PROCPLGPLAT | |
| SCHEMBL7215941 | 0.86 | F10 (0.46) | F10F2PROCPLGPLAT | |
| Hydrochloric Acid SCHEMBL7220011 | 0.85 | F10 (0.45) | F10F2PROCPLGPLAT | |
| Hydrochloric Acid SCHEMBL7220013 | 0.85 | F10 (0.45) | F10F2PROCPLGPLAT | |
| Trifluoroacetic Acid SCHEMBL6222162 | 0.84 | F10 (0.47) | F10F2ROCK1ROCK2KCNH2 | |
| Trifluoroacetic Acid SCHEMBL7414635 | 0.84 | F10 (0.47) | F10F2ROCK1ROCK2KCNH2 | |
| Trifluoroacetic Acid SCHEMBL7453367 | 0.84 | F10 (0.47) | F10F2ROCK1ROCK2KCNH2 | |
| SCHEMBL6221084 | 0.83 | F10 (0.44) | F10F2PROCPLGPLAT | |
| SCHEMBL7453305 | 0.83 | F10 (0.44) | F10F2PROCPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602864-B1 | Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-08-05 | — | — | US | disclosed |