Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216103 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4ERAB9AMAPTPKM | |
| SCHEMBL7216109 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4ERAB9AMAPTPKM | |
| SCHEMBL7219520 | 0.83 | TSHR (0.46) | SMN1; SMN2KDM4ERAB9AALDH1A1MEN1 | |
| SCHEMBL7219524 | 0.83 | TSHR (0.46) | SMN1; SMN2KDM4ERAB9AALDH1A1MEN1 | |
| SCHEMBL7219522 | 0.83 | TSHR (0.46) | SMN1; SMN2KDM4ERAB9AALDH1A1MEN1 | |
| SCHEMBL7216082 | 0.81 | KDM4E (0.43) | SMN1; SMN2KDM4ERAB9AALDH1A1MEN1 | |
| SCHEMBL7216094 | 0.81 | KDM4E (0.43) | SMN1; SMN2KDM4ERAB9AALDH1A1MEN1 | |
| SCHEMBL7216088 | 0.81 | KDM4E (0.43) | SMN1; SMN2KDM4ERAB9AALDH1A1MEN1 | |
| SCHEMBL7214682 | 0.73 | ALDH1A1 (0.56) | KDM4ERAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL7214686 | 0.73 | ALDH1A1 (0.56) | KDM4ERAB9AMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610692-B1 | Anticoagulants | MERCK & CO., INC. | 2003-08-26 | — | — | US | disclosed |