Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.65 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.60 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.60 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548385 | 0.88 | LPAR3 (0.77) | LPAR3LPAR2LPAR1ENPP2S1PR1 | |
| SCHEMBL7124930 | 0.88 | LPAR3 (0.77) | LPAR3LPAR2LPAR1ENPP2S1PR1 | |
| SCHEMBL7550150 | 0.88 | LPAR3 (0.73) | LPAR3LPAR2LPAR1ENPP2S1PR1 | |
| SCHEMBL7116031 | 0.88 | LPAR3 (0.77) | LPAR3LPAR2LPAR1ENPP2S1PR1 | |
| SCHEMBL8438271 | 0.88 | LPAR3 (0.77) | LPAR3LPAR2LPAR1ENPP2S1PR1 | |
| SCHEMBL8438260 | 0.88 | LPAR3 (0.77) | LPAR3LPAR2LPAR1ENPP2S1PR1 | |
| SCHEMBL5978775 | 0.86 | LPAR3 (0.62) | LPAR3LPAR2LPAR1ENPP2S1PR1 | |
| SCHEMBL7108271 | 0.85 | LPAR3 (0.66) | LPAR3LPAR2LPAR1ENPP2S1PR1 | |
| SCHEMBL9320338 | 0.85 | LPAR3 (0.66) | LPAR3LPAR2LPAR1ENPP2S1PR1 | |
| SCHEMBL27788145 | 0.85 | LPAR3 (0.66) | LPAR3LPAR2LPAR1ENPP2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161436-B1 | Polyunsaturated fatty acid derivatives and their use in the treatment of cancer | ARDENIA INVESTMENTS LTD (GI) | 2003-06-25 | — | — | EP | disclosed |