Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.73 |
| ▸ | ANPEP | P15144 | 2/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4672040 | 1.00 | EPHX1 (0.73) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| SCHEMBL5232841 | 1.00 | EPHX1 (0.73) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| SCHEMBL28656 | 0.85 | EPHX1 (1.00) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| Hydrochloric Acid SCHEMBL9402300 | 0.82 | EPHX1 (0.94) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| SCHEMBL6545954 | 0.82 | EPHX1 (0.67) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| SCHEMBL1928796 | 0.81 | ANPEP (1.00) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| SCHEMBL6805553 | 0.81 | ANPEP (1.00) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| SCHEMBL8778520 | 0.81 | EPHX1 (0.73) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| SCHEMBL43428 | 0.81 | EPHX1 (0.73) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| SCHEMBL859554 | 0.81 | ANPEP (1.00) | EPHX1ANPEPSLC6A2TAAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1314732-A2 | Substituted pyrimidine compounds and their use | AMGEN INC. (US) | 2003-05-28 | — | — | EP | disclosed |
| EP-1314731-A2 | Substituted pyrimidine compounds and their use | AMGEN INC. (US) | 2003-05-28 | — | — | EP | disclosed |