SCHEMBL43428

SCHEMBL43428

CCC(N)Cc1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.73
ANPEP P15144 1/20 0.61
SLC6A4 P31645 3/20 0.60
SLC6A2 P23975 2/20 0.60
TAAR1 Q96RJ0 2/20 0.60
MAOA P21397 1/20 0.60
SLC6A3 Q01959 1/20 0.60
SIGMAR1 Q99720 1/20 0.60
CYP2A6 P11509 1/20 0.60
ADORA2A P29274 1/20 0.60
ADORA1 P30542 1/20 0.60
CYP2D6 P10635 1/20 0.56
SCN4A P35499 2/20 0.50
TRPA1 O75762 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL895668 1.00 EPHX1 (0.73) EPHX1ANPEPSLC6A4SLC6A2TAAR1
SCHEMBL895787 1.00 EPHX1 (0.73) EPHX1ANPEPSLC6A4SLC6A2TAAR1
Hydrochloric Acid SCHEMBL8734599 0.98 EPHX1 (0.70) EPHX1ANPEPSLC6A4SLC6A2TAAR1
Hydrochloric Acid SCHEMBL8842804 0.98 EPHX1 (0.70) EPHX1ANPEPSLC6A4SLC6A2TAAR1
SCHEMBL17906518 0.87 SLC6A4 (0.56) EPHX1ANPEPSLC6A4SLC6A2TAAR1
SCHEMBL16945131 0.87 SLC6A4 (0.56) EPHX1ANPEPSLC6A4SLC6A2TAAR1
SCHEMBL8749872 0.87 EPHX1 (0.55) EPHX1ANPEPSLC6A4SLC6A2TAAR1
SCHEMBL6014598 0.85 EPHX1 (0.53) EPHX1ANPEPSLC6A4SLC6A2TAAR1
SCHEMBL28656 0.85 EPHX1 (1.00) EPHX1ANPEPSLC6A4SLC6A2TAAR1
SCHEMBL13696737 0.82 LTA4H (0.72) SLC6A2MAOASLC6A3SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 522 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028600-A1 TRANSAMINASE POLYPEPTIDES CODEXIS INC (US) 2026-01-29 US claimed
US-12448611-B2 Transaminase polypeptides CODEXIS, INC. (US) 2025-10-21 US claimed
US-20240150732-A1 TRANSAMINASE POLYPEPTIDES INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT 2024-05-09 US claimed
US-11939602-B2 Transaminase polypeptides INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT 2024-03-26 US claimed
WO-2023214011-A1 ENZYMATIC METHOD FOR PREPARING (R)-3-AMINO-4-ARYL-BUTANOIC ACID DERIVATIVES ENZYMICALS AG (DE) 2023-11-09 WO claimed
EP-4273254-A1 ENZYMATIC METHOD FOR PREPARING (R)-3-AMINO-4-ARYL-BUTANOIC ACID DERIVATIVES Enzymicals AG (DE) 2023-11-08 EP claimed
US-20230120624-A1 TRANSAMINASE POLYPEPTIDES INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT 2023-04-20 US claimed
US-11542485-B2 Transaminase polypeptides CODEXIS, INC. (US) 2023-01-03 US claimed
US-20220194969-A1 METAL HALIDE PEROVSKITE LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2022-06-23 US claimed
US-20210230564-A1 TRANSAMINASE POLYPEPTIDES INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT 2021-07-29 US claimed
WO-2013024453-A1 ENZYMATIC SYNTHESIS OF OPTICALLY ACTIVE CHIRAL AMINES EMBIO LIMITED (IN) 2013-02-21 WO claimed
CN-102574791-A Enzymatic transamination of cyclopamine analogs INFINITY PHARMACEUTICALS INC 2012-07-11 CN claimed
EP-2462115-A1 ENZYMATIC TRANSAMINATION OF CYCLOPAMINE ANALOGS Infinity Pharmaceuticals, Inc. (US) 2012-06-13 EP claimed
US-20120083607-A1 Enzymatic Transamination of Cyclopamine Analogs INFINITY PHARMACEUTICALS, INC. (US) 2012-04-05 US claimed
EP-2385983-A2 TRANSAMINASE POLYPEPTIDES Codexis, Inc. (US) 2011-11-16 EP claimed
US-D646886-S1 Tip of an umbrella Pro Performance Sports, L.L.C. (US) 2011-10-18 US claimed
WO-2011017551-A1 ENZYMATIC TRANSAMINATION OF CYCLOPAMINE ANALOGS INFINITY PHARMACEUTICALS, INC. (US) 2011-02-10 WO claimed
US-20100209981-A1 TRANSAMINASE POLYPEPTIDES CODEXIS, INC. (US) 2010-08-19 US claimed
WO-2010081053-A2 TRANSAMINASE POLYPEPTIDES CODEXIS, INC. (US) 2010-07-15 WO claimed
US-4423263-A REACTION WITH N-HALOGENAMINE IN PRESENCE OF PROTON DONOR AND METAL CATALYSTS ANIC, S.P.A. (IT) 1983-12-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220194969-A1 METAL HALIDE PEROVSKITE LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME HCN4, SLC46A1, FES EPHX1 3025/4885ANPEP 3505/4885SLC6A4 141/4885
US-20120083607-A1 Enzymatic Transamination of Cyclopamine Analogs TKT, TALDO1, BCHE EPHX1 406/4885ANPEP 103/4885SLC6A4 1280/4885
US-20260028600-A1 TRANSAMINASE POLYPEPTIDES GOT1, OAT, PEPD EPHX1 3023/4885ANPEP 75/4885SLC6A4 260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.