Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.55 |
| ▸ | ITGAV | P06756 | 8/20 | 0.55 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216234 | 1.00 | ITGB3 (0.55) | ITGB3ITGA2BITGAVITGB5MAPT | |
| SCHEMBL7216195 | 0.92 | ITGB3 (0.62) | ITGB3ITGA2BITGAVITGB5 | |
| SCHEMBL7217041 | 0.92 | ITGB3 (0.62) | ITGB3ITGA2BITGAVITGB5 | |
| SCHEMBL7218322 | 0.92 | ITGB3 (0.55) | ITGB3ITGA2BITGAVITGB5EPHX2 | |
| SCHEMBL7223767 | 0.91 | ITGB3 (0.54) | ITGB3ITGA2BITGAVITGB5EPHX2 | |
| SCHEMBL7221686 | 0.85 | ITGB3 (0.60) | ITGB3ITGA2BITGAVITGB5 | |
| SCHEMBL7221679 | 0.85 | ITGB3 (0.60) | ITGB3ITGA2BITGAVITGB5 | |
| SCHEMBL7667722 | 0.84 | MEN1 (0.42) | ITGB3ITGA2BITGAVMAPTL3MBTL1 | |
| SCHEMBL7667715 | 0.84 | MEN1 (0.42) | ITGB3ITGA2BITGAVMAPTL3MBTL1 | |
| SCHEMBL1802005 | 0.82 | ITGB3 (0.59) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602878-B1 | Acylquanidine derivatives, method for preparing same, application as medicines and pharmaceutical compositions containing them | AVENTIS PHARMA S.A. (FR) | 2003-08-05 | — | — | US | claimed |
| US-6602878-B1 | Acylquanidine derivatives, method for preparing same, application as medicines and pharmaceutical compositions containing them | AVENTIS PHARMA S.A. (FR) | 2003-08-05 | — | — | US | disclosed |