⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclooctane SCHEMBL30978275 | 1.00 | TSHR (0.64) | — | |
| Cyclohexane SCHEMBL129222 | 1.00 | TSHR (0.64) | — | |
| Hexane SCHEMBL5073928 | 1.00 | TSHR (0.64) | — | |
| Cyclohexane SCHEMBL10454605 | 1.00 | TSHR (0.64) | — | |
| Cyclohexane SCHEMBL5787824 | 1.00 | TSHR (0.64) | — | |
| Cyclohexane SCHEMBL10453382 | 1.00 | TSHR (0.64) | — | |
| Cyclohexane SCHEMBL12475770 | 1.00 | TSHR (0.64) | — | |
| Hexane SCHEMBL18764545 | 1.00 | TSHR (0.64) | — | |
| Cyclohexane SCHEMBL11423653 | 1.00 | TSHR (0.64) | — | |
| Cyclohexane SCHEMBL10572382 | 1.00 | TSHR (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030003055-A1 | Methods of preparing gaseous precursor-filled microspheres | BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC. | 2003-01-02 | — | — | US | disclosed |
| US-6479034-B1 | Method of preparing gas and gaseous precursor-filled microspheres | BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1252885-A2 | Methods of preparing gas and gaseous precursor-filled microspheres | IMARX PHARMACEUTICAL CORP. (US) | 2002-10-30 | — | — | EP | disclosed |
| US-20020150539-A1 | Ultrasound imaging and treatment | UNGER EVAN C (US) | 2002-10-17 | — | — | US | disclosed |
| US-6071495-A | TEMPERATURE ACTIVATED; PARTICULARLY USEFUL, FOR EXAMPLE, IN ULTRASONIC IMAGING APPLICATIONS AND IN THERAPEUTIC DRUG DELIVERY SYSTEMS. | IMARX PHARMACEUTICAL CORP. (US) | 2000-06-06 | — | — | US | disclosed |
| US-5853752-A | Methods of preparing gas and gaseous precursor-filled microspheres | IMARX PHARMACEUTICAL CORP. (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0712293-A4 | METHODS OF PREPARING GAS AND GASEOUS PRECURSOR-FILLED MICROSPHERES | UNGER EVAN C (US) | 1998-05-06 | — | — | EP | disclosed |
| EP-0712293-A1 | METHODS OF PREPARING GAS AND GASEOUS PRECURSOR-FILLED MICROSPHERES | UNGER, Evan C (US) | 1996-05-22 | — | — | EP | disclosed |
| WO-1994028780-A2 | METHODS OF PREPARING GAS AND GASEOUS PRECURSOR-FILLED MICROSPHERES | UNGER EVAN C (US) | 1994-12-22 | — | — | WO | disclosed |