Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.61 |
| ▸ | ITGAV | P06756 | 16/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212703 | 0.85 | ITGB3 (0.83) | ITGB3ITGAVITGA2B | |
| SCHEMBL7217699 | 0.79 | ITGB3 (0.51) | ITGB3ITGAVITGA2BLMNAPOLB | |
| SCHEMBL7211510 | 0.77 | ITGB3 (0.52) | ITGB3ITGAVITGA2BLMNAPOLB | |
| SCHEMBL7217678 | 0.74 | ITGB3 (0.54) | ITGB3ITGAVITGA2BLMNAPOLB | |
| SCHEMBL7217600 | 0.73 | ITGB3 (0.93) | ITGB3ITGAVITGA2B | |
| SCHEMBL7216459 | 0.72 | ITGB3 (0.66) | ITGB3ITGAVITGA2BLMNAPOLB | |
| SCHEMBL7211537 | 0.72 | ITGB3 (0.91) | ITGB3ITGAVITGA2B | |
| SCHEMBL7212645 | 0.70 | ITGB3 (0.60) | ITGB3ITGAVITGA2BLMNAPOLB | |
| SCHEMBL7217507 | 0.70 | ITGB3 (0.87) | ITGB3ITGAVITGA2B | |
| SCHEMBL7974527 | 0.70 | ITGB3 (0.87) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620820-B2 | Imidazole dione or one, thione derivatives as antitumor and antiinflammatory agents, also treats cardiovascular disease, nephropathies and retinopathies | HOECHST AKTIENGESELLSCHAFT (DE) | 2003-09-16 | — | — | US | disclosed |
| US-6218415-B1 | THERAPY OF BONE REABSORPTION BY OSTEOCLASTS, TUMOR GROWTH AND TUMOR METASTASIS, INFLAMMATION, CARDIOVASCULAR DISEASE, NEPHROPATHIES AND RETINOPATHIES | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-04-17 | — | — | US | disclosed |