Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.56 |
| ▸ | HTR2C | P28335 | 9/20 | 0.56 |
| ▸ | MAOA | P21397 | 7/20 | 0.56 |
| ▸ | KDM1A | O60341 | 5/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.56 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187439 | 1.00 | MAOB (0.56) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL21111934 | 1.00 | MAOB (0.56) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL20195820 | 1.00 | MAOB (0.56) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| Ammonia Solution, Strong SCHEMBL266310 | 0.97 | MAOB (0.54) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL9228291 | 0.91 | MAOB (0.48) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL11851470 | 0.87 | MAOB (0.56) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL5682494 | 0.82 | MAOB (0.45) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL5682467 | 0.82 | MAOB (0.45) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL8845464 | 0.79 | MAOB (0.65) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL10540521 | 0.79 | MAOB (0.65) | MAOBHTR2CMAOAKDM1ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081923-A1 | PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF | Frequency Therapeutics, Inc. (US) | 2023-05-11 | — | — | WO | disclosed |
| US-6503898-B1 | Administering 4,7-dibenzyl-5,6-dihydroxy-N,N*-di(m-aminobenzyl)--1,3-diazepin-2-one or salt to treat human immunodeficiency virus infection | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-01-07 | — | — | US | disclosed |
| EP-0396710-A1 | PROCESS FOR THE SELECTIVE EXCITATION OF NMR SIGNALS. | SPECTROSPIN AG (CH) | 1990-11-14 | — | — | EP | disclosed |
| US-4255595-A | Optically active cyclooctenyl ethyl alcohol | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1981-03-10 | — | — | US | disclosed |
| US-4152366-A | POLYMERIZABLE TO OPTICALLY ACTIVE POLYMERS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1979-05-01 | — | — | US | disclosed |
| US-4098834-A | Optically active 3-substituted cyclooctene bicyclo-[6.0.3.]-undecene-3 and exo-2-vinyl norbornane | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1978-07-04 | — | — | US | disclosed |
| US-3978147-A | NI, LEWIS ACID, PHOSPHINE | STUDIENGESELLSCHAFT KOHLE M.B.H (DT) | 1976-08-31 | — | — | US | disclosed |