Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.56 |
| ▸ | HTR2C | P28335 | 9/20 | 0.56 |
| ▸ | MAOA | P21397 | 7/20 | 0.56 |
| ▸ | KDM1A | O60341 | 5/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.56 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216730 | 1.00 | MAOB (0.56) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL21111934 | 1.00 | MAOB (0.56) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL20195820 | 1.00 | MAOB (0.56) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| Ammonia Solution, Strong SCHEMBL266310 | 0.97 | MAOB (0.54) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL9228291 | 0.91 | MAOB (0.48) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL11851470 | 0.87 | MAOB (0.56) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL5682494 | 0.82 | MAOB (0.45) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL5682467 | 0.82 | MAOB (0.45) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL8845464 | 0.79 | MAOB (0.65) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL10540521 | 0.79 | MAOB (0.65) | MAOBHTR2CMAOAKDM1ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102300550-A | Perfume systems | — | 2011-12-28 | — | — | CN | claimed |
| US-20070049594-A1 | Novel compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-03-01 | — | — | US | claimed |
| US-6723743-B1 | TREATING PATIENT SUFFERING FROM RHEUMATOID ARTHRITIS, PSORIASIS, BRONCHIAL ASTHMA, ALZHEIMER'S DISEASE, MYOCARDIAL INFARCTION OR ATHEROSCLEROSIS | NEUROGEN CORPORATION | 2004-04-20 | — | — | US | claimed |
| EP-1383748-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-01-28 | — | — | EP | claimed |
| WO-2002051983-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-07-04 | — | — | WO | claimed |
| CN-118993931-A | Method for synthesizing beta-azido ketone compound | 山东第一医科大学(山东省医学科学院) | 2024-11-22 | — | — | CN | disclosed |
| CN-116730784-A | Synthesis method of malonic acid derivative | 华南理工大学 | 2023-09-12 | — | — | CN | disclosed |
| WO-2023121992-A1 | CYCLOPROPYL COMPOUNDS | ICAGEN, LLC (US) | 2023-06-29 | — | — | WO | disclosed |
| EP-3495349-B1 | (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2023-06-28 | — | — | EP | disclosed |
| CN-115968934-A | Method for preserving eggs and improving quality of egg content | 铁骑力士食品有限责任公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-113456626-B | Xanthine oxidase inhibitor and screening method and application thereof | 吉林大学 | 2022-05-06 | — | — | CN | disclosed |
| CN-113456626-A | Xanthine oxidase inhibitor and screening method and application thereof | 吉林大学 | 2021-10-01 | — | — | CN | disclosed |
| US-5262417-A | Antibacterial quinolone compounds | THE UPJOHN COMPANY (US) | 1993-11-16 | — | — | US | disclosed |
| US-5260316-A | Lipoxygenase inhibitor | CIBA-GEIGY CORPORATION (US) | 1993-11-09 | — | — | US | disclosed |
| EP-0526402-A1 | Heteroaryl substituted hydroxylamine derivatives as lipoxygenase inhibitors | CIBA-GEIGY AG (CH) | 1993-02-03 | — | — | EP | disclosed |
| WO-1990006307-A2 | ANTIBACTERIAL QUINOLONE COMPOUNDS | THE UPJOHN COMPANY (US) | 1990-06-14 | — | — | WO | disclosed |
| US-4255595-A | Optically active cyclooctenyl ethyl alcohol | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1981-03-10 | — | — | US | disclosed |
| US-4152366-A | POLYMERIZABLE TO OPTICALLY ACTIVE POLYMERS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1979-05-01 | — | — | US | disclosed |
| US-4098834-A | Optically active 3-substituted cyclooctene bicyclo-[6.0.3.]-undecene-3 and exo-2-vinyl norbornane | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1978-07-04 | — | — | US | disclosed |
| US-3978147-A | NI, LEWIS ACID, PHOSPHINE | STUDIENGESELLSCHAFT KOHLE M.B.H (DT) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049594-A1 | Novel compounds and compositions as cathepsin inhibitors | CTSS, CTSB, CTSE | MAOB 335/4885HTR2C 4435/4885MAOA 490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.