Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.47 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | PROC | P04070 | 1/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.38 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218777 | 0.92 | F2 (0.51) | F2F10PRSS1 | |
| SCHEMBL7223072 | 0.89 | F2 (0.51) | F2 | |
| SCHEMBL7120809 | 0.89 | F2 (0.47) | F2F10NQO2SLC22A2PLG | |
| SCHEMBL7119786 | 0.89 | F2 (0.47) | F2F10NQO2SLC22A2PLG | |
| SCHEMBL7222782 | 0.88 | F2 (0.47) | F2F10NQO2SLC22A2PLG | |
| Hydrochloric Acid SCHEMBL7436617 | 0.87 | F2 (0.49) | F2F10NQO2SLC22A2PLG | |
| Hydrochloric Acid SCHEMBL7438141 | 0.87 | F2 (0.49) | F2F10NQO2SLC22A2PLG | |
| SCHEMBL7224489 | 0.87 | F2 (0.51) | F2 | |
| Hydrochloric Acid SCHEMBL7439048 | 0.86 | F2 (0.52) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7431110 | 0.86 | F2 (0.53) | F2F10NQO2SLC22A2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6656956-B2 | Tryptase inhibitor; antiinflamamtory agents, antiallergens | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-12-02 | — | — | US | disclosed |