Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7217499 | 0.94 | F2 (0.42) | F2HTR2AKDM4EALDH1A1TDP1 | |
| SCHEMBL7223072 | 0.92 | F2 (0.51) | F2HDAC1 | |
| SCHEMBL7218777 | 0.91 | F2 (0.51) | F2 | |
| SCHEMBL7118128 | 0.90 | F2 (0.49) | F2KDM4E | |
| Hydrochloric Acid SCHEMBL7439048 | 0.89 | F2 (0.52) | F2KDM4E | |
| SCHEMBL7115891 | 0.87 | F2 (0.46) | F2HDAC1 | |
| SCHEMBL7124406 | 0.87 | F2 (0.47) | F2KDM4E | |
| SCHEMBL7115903 | 0.87 | F2 (0.46) | F2 | |
| SCHEMBL7120411 | 0.87 | F2 (0.46) | F2KDM4E | |
| SCHEMBL7117072 | 0.87 | F2 (0.46) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6656956-B2 | Tryptase inhibitor; antiinflamamtory agents, antiallergens | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-12-02 | — | — | US | disclosed |