Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.47 |
| ▸ | ITGAV | P06756 | 19/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.47 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7217610 | 0.92 | ITGB3 (0.47) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7211540 | 0.92 | ITGB3 (0.46) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7211648 | 0.91 | ITGB3 (0.52) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7211451 | 0.87 | ITGB3 (0.47) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7217767 | 0.86 | ITGB3 (0.44) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7211465 | 0.86 | ITGB3 (0.42) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7212704 | 0.85 | ITGB3 (0.42) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7217733 | 0.84 | ITGB3 (0.40) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7961029 | 0.81 | ITGB3 (0.51) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7211463 | 0.81 | ITGB3 (0.41) | ITGB3ITGAVITGA2BITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620820-B2 | Imidazole dione or one, thione derivatives as antitumor and antiinflammatory agents, also treats cardiovascular disease, nephropathies and retinopathies | HOECHST AKTIENGESELLSCHAFT (DE) | 2003-09-16 | — | — | US | disclosed |