Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 14/20 | 0.90 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.90 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.90 |
| ▸ | TP53 | P04637 | 3/20 | 0.90 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.90 |
| ▸ | TSHR | P16473 | 1/20 | 0.90 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.90 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.90 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.90 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.87 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.87 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.87 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.87 |
| ▸ | HPGD | P15428 | 2/20 | 0.87 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.87 |
| ▸ | MEN1 | O00255 | 2/20 | 0.87 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.87 |
| ▸ | HTT | P42858 | 1/20 | 0.87 |
| ▸ | GFER | P55789 | 1/20 | 0.87 |
| ▸ | POLB | P06746 | 3/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216645 | 0.86 | GAA (0.82) | GAAKDM4EALDH1A1TP53ALOX15 | |
| SCHEMBL19002480 | 0.78 | GAA (0.79) | GAAKDM4EALDH1A1TP53ALOX15 | |
| SCHEMBL24367734 | 0.76 | GAA (0.72) | GAAKDM4EALDH1A1TP53ALOX15 | |
| SCHEMBL7221613 | 0.75 | ATP1A1 (1.00) | GAAKDM4EALDH1A1TP53ALOX15 | |
| SCHEMBL28751568 | 0.74 | GAA (0.64) | GAAKDM4EALDH1A1TP53ALOX15 | |
| SCHEMBL27580098 | 0.74 | GAA (0.64) | GAAKDM4EALDH1A1TP53ALOX15 | |
| SCHEMBL7218018 | 0.74 | ATP1A1 (0.78) | GAAKDM4EALDH1A1TP53ALOX15 | |
| SCHEMBL6645694 | 0.73 | GAA (0.61) | GAAKDM4EALDH1A1TP53ALOX15 | |
| SCHEMBL6780737 | 0.73 | GAA (0.61) | GAAKDM4EALDH1A1TP53ALOX15 | |
| SCHEMBL13234269 | 0.72 | FYN (0.80) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596739-B2 | Anticarcinogenic agents, cardiovascular disorders and antiinflammatory agents | THE PROCTER & GAMBLE COMPANY | 2003-07-22 | — | — | US | claimed |