Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 8/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28701891 | 0.81 | F10 (0.66) | MAPTPKMRAB9ANPC1NFKB1 | |
| SCHEMBL20022682 | 0.78 | RAB9A (0.59) | MAPTPKMRAB9ANPC1NFKB1 | |
| SCHEMBL92266 | 0.75 | RAB9A (0.62) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL29175040 | 0.74 | SMN1; SMN2 (0.66) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL14389186 | 0.73 | RAB9A (0.56) | MAPTPKMRAB9ANPC1NFKB1 | |
| SCHEMBL18844916 | 0.71 | RAB9A (0.74) | MAPTPKMRAB9ANPC1MEN1 | |
| SCHEMBL91651 | 0.70 | RAB9A (0.56) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL91534 | 0.70 | MAOB (0.60) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL10273857 | 0.70 | NPC1 (0.54) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL92350 | 0.70 | NPC1 (0.57) | MAPTRAB9ANPC1NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |