Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | TYR | P14679 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28503495 | 0.92 | HSPA5 (0.38) | HSPA5CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL21384992 | 0.87 | HSPA5 (0.41) | HSPA5CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL6065585 | 0.87 | CYP2C19 (0.43) | HSPA5CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL31169458 | 0.86 | HSPA5 (0.40) | HSPA5CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL28082100 | 0.85 | NPC1 (0.49) | HSPA5CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL9504918 | 0.84 | PGK1 (0.37) | HSPA5CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL11457863 | 0.83 | PGK1 (0.36) | HSPA5CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL27623644 | 0.83 | NR5A2 (0.36) | HSPA5CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL9421246 | 0.83 | HSPA5 (0.38) | HSPA5CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL28417776 | 0.83 | SMN1; SMN2 (0.39) | HSPA5CYP2C9CYP2C19SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6649770-B1 | Exhibit superior hydrolytic stability, handling and storage stability as well as good resistance to extractability when present in stabilized composition | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-11-18 | — | — | US | disclosed |
| US-5475042-A | Stabilizer for organic polymer promoting heat, radiation and oxidation resistance | CIBA-GEIGY CORPORATION (US) | 1995-12-12 | — | — | US | disclosed |