Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | PGD | P52209 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12846719 | 0.91 | TDP1 (0.75) | TDP1ABCB1PGDALDH1A1TSHR | |
| SCHEMBL8723281 | 0.91 | TDP1 (0.75) | TDP1ABCB1PGDALDH1A1TSHR | |
| SCHEMBL7150206 | 0.91 | TDP1 (0.75) | TDP1ABCB1PGDALDH1A1TSHR | |
| SCHEMBL31029931 | 0.90 | TDP1 (0.81) | TDP1ABCB1PGDALDH1A1TSHR | |
| SCHEMBL8600016 | 0.90 | TDP1 (0.81) | TDP1ABCB1PGDALDH1A1TSHR | |
| SCHEMBL2100980 | 0.88 | TDP1 (0.67) | TDP1ABCB1PGDALDH1A1TSHR | |
| SCHEMBL6817132 | 0.88 | TDP1 (0.67) | TDP1ABCB1PGDALDH1A1TSHR | |
| SCHEMBL7792932 | 0.88 | TDP1 (0.67) | TDP1ABCB1PGDALDH1A1TSHR | |
| SCHEMBL9577881 | 0.85 | TDP1 (0.62) | TDP1ABCB1ALDH1A1TSHRLMNA | |
| SCHEMBL20607560 | 0.85 | TDP1 (0.73) | TDP1ABCB1ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1356033-A2 | METHYL-D-ERYTHRITOL PHOSPHATE PATHWAY GENES | Monsanto Technology LLC (US) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002012478-A2 | METHYL-D-ERYTHRITOL PHOSPHATE PATHWAY GENES | MONSANTO TECHNOLOGY, LLC (US) | 2002-02-14 | — | — | WO | disclosed |