Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GALR2 | O43603 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17378851 | 0.87 | NPSR1 (0.45) | NPSR1MAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL7219587 | 0.83 | ALDH1A1 (0.48) | NPSR1MAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL9807534 | 0.77 | NPSR1 (0.50) | NPSR1MAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL31125083 | 0.77 | SMN1; SMN2 (0.51) | NPSR1MAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL3456598 | 0.77 | HTT (0.62) | MAPTHTTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL520594 | 0.77 | SMN1; SMN2 (0.54) | MAPTHTTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL3544173 | 0.77 | SMN1; SMN2 (0.51) | NPSR1MAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL6597670 | 0.75 | AR (0.47) | NPSR1MAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL2646601 | 0.74 | MAPK1 (0.71) | NPSR1MAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL7223930 | 0.74 | GAA (0.45) | NPSR1MAPTHTTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |