Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.61 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.48 |
| ▸ | TACR2 | P21452 | 4/20 | 0.47 |
| ▸ | ACACB | O00763 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7223448 | 0.86 | CNR2 (0.65) | CNR2TRPV4TACR2CNR1CAPN1 | |
| SCHEMBL7218551 | 0.82 | CNR2 (0.60) | CNR2TRPV4TACR2ACACBCNR1 | |
| SCHEMBL7218747 | 0.81 | CNR2 (0.47) | CNR2TRPV4TACR2CNR1CAPN1 | |
| Morforex SCHEMBL1818022 | 0.71 | SIGMAR1 (0.54) | CNR1 | |
| SCHEMBL24863052 | 0.70 | ACACB (0.63) | ACACBNPC1RAB9AALDH1A1 | |
| SCHEMBL7217580 | 0.69 | CNR2 (0.69) | CNR2TRPV4TACR2CNR1 | |
| SCHEMBL13164066 | 0.69 | KDM4E (0.61) | NPC1ALDH1A1 | |
| SCHEMBL24862898 | 0.69 | NPC1 (0.63) | NPC1RAB9A | |
| SCHEMBL24609344 | 0.66 | NPC1 (0.79) | NPC1RAB9AALDH1A1 | |
| SCHEMBL2543698 | 0.66 | NPC1 (0.79) | NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653304-B2 | Antiarthritic agents; skin disorders; anticarcinogenic agents | BRISTOL-MYERS SQUIBB CO. | 2003-11-25 | — | — | US | disclosed |