Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 10/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218772 | 1.00 | CRHR1 (0.58) | CRHR1 | |
| SCHEMBL7216722 | 0.89 | CRHR1 (0.54) | CRHR1 | |
| SCHEMBL7217257 | 0.89 | CRHR1 (0.54) | CRHR1 | |
| SCHEMBL7217253 | 0.89 | CRHR1 (0.54) | CRHR1 | |
| SCHEMBL7629851 | 0.81 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL7218557 | 0.76 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL7227483 | 0.75 | CRHR1 (0.74) | CRHR1 | |
| SCHEMBL7227480 | 0.75 | CRHR1 (0.74) | CRHR1 | |
| SCHEMBL7217467 | 0.75 | CRHR1 (0.86) | CRHR1 | |
| SCHEMBL7217464 | 0.75 | CRHR1 (0.86) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6525056-B2 | A fused nitrogen containing heterocyclic compound useful for treating psychiatric and neurological disorders, anxiety, post-traumatic stress, supranuclear palsy, feeding, immunological, cardiovascular and hypersensitivity disorders | BRISTOL-MYERS SQUIBB COMPANY | 2003-02-25 | — | — | US | disclosed |