SCHEMBL7218838

SCHEMBL7218838

C(=Cc1ccc(N(c2ccccc2)c2c3ccccc3c(-c3c4ccccc4c(N(c4ccccc4)c4ccc(C=Cc5ccccc5)cc4)c4ccccc34)c3ccccc23)cc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 3/20 0.48
APP P05067 1/20 0.44
MAOB P27338 2/20 0.39
NFE2L2 Q16236 1/20 0.39
CYP19A1 P11511 1/20 0.39
MAOA P21397 1/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
TRPA1 O75762 1/20 0.36
ALDH1A1 P00352 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
MAPT P10636 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
MAPK1 P28482 2/20 0.36
USP2 O75604 1/20 0.36
CTNNB1 P35222 1/20 0.36
ATM Q13315 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
TRPM8 Q7Z2W7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10128935 0.94 RELA (0.53) RELAAPPMAOBNFE2L2CYP19A1
SCHEMBL9971875 0.94 RELA (0.53) RELAAPPMAOBNFE2L2CYP19A1
SCHEMBL3417058 0.94 RELA (0.53) RELAAPPMAOBNFE2L2CYP19A1
SCHEMBL7218059 0.90 RELA (0.47) RELAAPPNFE2L2CTDSP1TRPA1
SCHEMBL12032089 0.90 APP (0.43) RELAAPPMAOBNFE2L2CYP19A1
SCHEMBL13021484 0.88 APP (0.45) RELAAPPMAOBNFE2L2CYP19A1
SCHEMBL14537298 0.86 RELA (0.42) RELAAPPNFE2L2CTDSP1ALDH1A1
SCHEMBL14537294 0.86 RELA (0.42) RELAAPPNFE2L2CTDSP1ALDH1A1
SCHEMBL9971970 0.86 RELA (0.48) RELAAPPMAOBNFE2L2CYP19A1
SCHEMBL9971944 0.85 RELA (0.49) RELAAPPMAOBNFE2L2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6582837-B1 Device having one or more organic thin layers including luminescent layer between anode and cathode, wherein at least one layer contains selected compound or compounds; exhibits higher-luminance luminescence than conventional device NEC CORPORATION (JP) 2003-06-24 US disclosed