Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562649 | 0.68 | PPOX (0.45) | PPOXMAPTTP53TSHRGAA | |
| SCHEMBL8523910 | 0.68 | PPOX (0.42) | PPOXMAPTTP53TSHRGAA | |
| SCHEMBL7918650 | 0.67 | PPOX (0.44) | PPOXMAPTTP53TSHRGAA | |
| Sulfentrazone SCHEMBL44683 | 0.66 | PPOX (1.00) | PPOX | |
| Sulfentrazone SCHEMBL18489655 | 0.66 | PPOX (1.00) | PPOX | |
| SCHEMBL11603971 | 0.66 | MCL1 (0.50) | PPOXMAOBHPGDPTGS1PTGS2 | |
| Sulfentrazone SCHEMBL28519794 | 0.65 | PPOX (0.98) | PPOX | |
| Sulfentrazone SCHEMBL20723669 | 0.65 | PPOX (0.98) | PPOX | |
| Sulfentrazone SCHEMBL29195861 | 0.65 | PPOX (0.98) | PPOX | |
| SCHEMBL30958745 | 0.65 | PPOX (0.85) | PPOXMAOBGAAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617281-B1 | Substituted acylamino phenyl uracils | BAYER AKTIENGESELLSCHAFT (DE) | 2003-09-09 | — | — | US | disclosed |